| Phase I |
CYP |
cytochrome P450 |
|
| CYP1A2 |
cytochrome P450, family 1, subfamily A, polypeptide 2 |
15q24 |
| CYP2A6 |
cytochrome P450, family 2, subfamily A, polypeptide 6 |
19q13.2 |
| CYP2B6 | cytochrome P450, family 2, subfamily B, polypeptide 6 |
19q13.2 |
| CYP2C8 |
cytochrome P450, family 2, subfamily C, polypeptide 8 |
10q23.33 |
| CYP2C9 |
cytochrome P450, family 2, subfamily C, polypeptide 9 |
10q24 |
| CYP2C19 |
cytochrome P450, family 2, subfamily C, polypeptide 19 |
10q24.1-q24.3 |
| CYP2D6 |
cytochrome P450, family 2, subfamily D, polypeptide 6 |
22q13.1 |
| CYP2J2 |
cytochrome P450, family 2, subfamily J, polypeptide 2 |
1p31.3-p31.2 |
| CYP2S1 |
cytochrome P450, family 2, subfamily S, polypeptide 1 |
19q13.1 |
| CYP3A4 |
cytochrome P450, family 3, subfamily A, polypeptide 4 |
7q21.1 |
| CYP3A5 |
cytochrome P450, family 3, subfamily A, polypeptide 5 |
7q21.1 |
| CYP3A7 |
cytochrome P450, family 3, subfamily A, polypeptide 7 |
7q21-q22.1 |
| Phase II |
UGT1A1 |
UDP glucuronosyltransferase 1 family, polypeptide A1 |
2q37 |
| UGT1A3 |
UDP glucuronosyltransferase 1 family, polypeptide A3 |
2q37 |
| UGT1A4 |
UDP glucuronosyltransferase 1 family, polypeptide A4 |
2q37 |
| UGT1A5 |
UDP glucuronosyltransferase 1 family, polypeptide A5 |
2q37 |
| UGT1A6 |
UDP glucuronosyltransferase 1 family, polypeptide A6 |
2q37 |
| UGT1A7 |
UDP glucuronosyltransferase 1 family, polypeptide A7 |
2q37 |
| UGT1A8 |
UDP glucuronosyltransferase 1 family, polypeptide A8 |
2q37 |
| UGT1A9 |
UDP glucuronosyltransferase 1 family, polypeptide A9 |
2q37 |
| UGT1A10 |
UDP glucuronosyltransferase 1 family, polypeptide A10 |
2q37 |
| TPMT |
thiopurine S-methyltransferase |
6p22.3 |
| SULT1A1 |
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 |
16p12.1 |
| SULT1A2 |
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 |
16p12.1 |
| SULT1A3 |
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 |
16p11.2 |
| Transcription factor |
NR1H3(LXRA) |
nuclear receptor subfamily 1, group H, member 3 |
11p11.2 |
| TCF1 |
HNF1 homeobox A |
12q24.2 |
| NR1H4 |
nuclear receptor subfamily 1, group H, member 4 |
12q23.1 |
| NR1I2 |
nuclear receptor subfamily 1, group I, member 2 |
3q12-q13.3 |
| Transporter |
ABCB1 |
?ATP-binding cassette, sub-family B (MDR/TAP), member 1 |
7q21.1 |
| ABCG2 |
ATP-binding cassette, sub-family G (WHITE), member 2 |
4q22 |
| SLC22A1 |
solute carrier family 22 (organic cation transporter), member 1 |
6q26 |
| SLC22A2 |
solute carrier family 22 (organic cation transporter), member 2 |
6q26 |
| SLC22A3 |
solute carrier family 22 (extraneuronal monoamine transporter), member 3 |
6q26-q27 |
| SLC22A6 |
solute carrier family 22 (organic anion transporter), member 6 |
11q13.1-q13.2 |
| SLC22A7 |
solute carrier family 22 (organic anion transporter), member 7 |
6p21.2-p21.1 |
| Other |
hOAT7 |
|
|
| POR |
P450 (cytochrome) oxidoreductase |
7q11.2 |
| ECGF |
|
|
| TYMS |
thymidylate synthetase |
18p11.32 |
