INJE PharmacoGenomics Research Center

· Han EH, Hwang YP, Jeong TC, Lee SS, Shin JG, Jeong HG.

Eugenol inhibit 7,12-dimethylbenz[a]anthracene-induced genotoxicity in MCF-7 cells: Bifunctional effects on CYP1 and NAD(P)H:quinone oxidoreductase. ()

FEBS Lett. 2007 Feb 20;581(4):749-56 [LINK]

2007-International

· Lee SJ, van der Heiden IP, Goldstein JA, van Schaik RH.

A new CYP3A5 variant, CYP3A5*11, is shown to be defective in nifedipine metabolism in a recombinant cDNA expression system. ()

Drug Metab Dispos. 2007 Jan;35(1):67-71. [LINK]

2006-International

· Shin JG, Kang WK, Shon JH, Arefayene M, Yoon YR, Kim KA, Kim DI, Kim DS, Cho KH, Woosley RL, Flockhart DA.

Possible interethnic differences in quinidine-induced QT prolongation between healthy Caucasian and Korean subjects. ()

Br J Clin Pharmacol. 2007 Feb;63(2):206-15. [LINK]

2006-International

· Kim KA, Park PW, Lee OJ, Choi SH, Min BH, Shin KH, Chun BG, Shin JG, Park JY.

Effect of CYP3A5*3 genotype on the pharmacokinetics and pharmacodynamics of amlodipine in healthy Korean subjects. ()

Clin Pharmacol Ther. 2006 Dec;80(6):646-56. [LINK]

2006-International

· Gwak J, Cho M, Gong SJ, Won J, Kim DE, Kim EY, Lee SS, Kim M, Kim TK, Shin JG, Oh S.

Protein-kinase-C-mediated {beta}-catenin phosphorylation negatively regulates the Wnt/{beta}-catenin pathway. (PRCDM)

J Cell Sci. 2006 Nov 15;119(Pt 22):4702-9. [LINK]

2006-International

· Yea SS, Jeong HS, Choi CY, Park KR, Oh S, Shin JG, Yun CH.

Inhibitory effect of anethole on T-lymphocyte proliferation and interleukin-2 production through down-regulation of the NF-AT and AP-1. ()

Toxicol In Vitro. 2006 Oct;20(7):1098-105. [LINK]

2006-International

· Liu KH, Kim MG, Lee DJ, Yoon YJ, Kim MJ, Shon JH, Choi CS, Choi YK, Desta Z, Shin JG.

Characterization of ebastine, hydroxyebastine, and carebastine metabolism by human liver microsomes and expressed cytochrome P450 enzymes: major roles for CYP2J2 and CYP3A. (NRL)

Drug Metab Dispos. 2006 Nov;34(11):1793-7. [LINK]

2006-International

· Shin JG, Lee KH, Fabio Leonessa, Robert Clarke,David Alastair Flockhart

The disposition of reduced haloperidol and HPP+ Metabolites of haloperidol, is not influenced by P-Glycoprotein ()

Kor J Clin Pharmacol Ther. 14(1): 42-50 [LINK ]

2006-Domestic

· Lee SJ, Shin JG

CYP2C9 Pharmacogenomics: Recent Update and Clinical Relevance. ()

Kor J Clin Pharmacol Ther. 14(1): 3-16 [LINK ]

2006-Domestic

· Liu KH, Moon JK, Seo JS, Park BS, Koo SJ, Lee HS, Kim JH.

Characterization of Pyribenzoxim Metabolizing Enzymes in Rat Liver (PRCDM)

한국독성학회, 22(1), 1-8 [LINK ]

2006-Domestic

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