INJE PharmacoGenomics Research Center

· Lee SJ, Kim WY, Kim H, Shon JH, Lee SS, Shin JG

Identification of new CYP2C19 variants exhibiting decreased enzyme activity in the metabolism of S-mephenytoin and omeprazole (BMRC, PRCDM)

Drug Metab Dispos. / 37(11):2262-9 [LINK]

2009-International

· Sugiyama E, Lee SJ, Lee SS, Kim WY, Kim SR, Tohkin M, Hasegawa R, Okuda H, Kawamoto M, Kamatani N, Sawada J, Kaniwa N, Saito Y, Shin JG

Ethnic Differences of two Non-synonymous Single Nucleotide Polymorphisms in CDA Gene (BMRC, Japan Fund)

Drug Metab. Pharmacokinet. / 24(6):553?556 [LINK]

2009-International

· Gwak JS, Song T, Song JY, Yun YS, Choi IW, Jeong Y, Shin JG, Oh S

Isoreserpine promotes beta-catenin degradation via Siah-1 up-regulation in HCT116 colon cancer cells. ()

Biochem Biophys Res Commun (3):444-449 2.750 [LINK]

2009-International

· Kim KB, Lee DJ, Yeo CW, Shin JG, Bae SK

Simultaneous quantification of rosiglitazone and its two major metabolites, N-desmethyl and p-hydroxy rosiglitazone in human plasma by liquid chromatography/tandem mass spectrometry: Application to an pharmacokinetic study (BMRC)

J Chromatogr B Analyt Technol Biomed Life Sci. 877(20-21):1951-6, 2009 Jul 1 [LINK]

2009-International

· Lee SJ, Lee SS, Jung HJ, Kim HS, Park SJ, Yeo CW, Shin JG

Discovery of novel functional variants and extensive evaluation of CYP2D6 genetic polymorphisms in Koreans (BMRC, PRCDM)

Drug Metab Dispos. 37(7):1464-70, 2009 Jul [LINK ]

2009-International

· Bae SK, Kim MJ, Shim EJ, Cho DY, Shon JH, Liu KH, Kim EY, Shin JG

HPLC determination of irbesartan in human plasma: its application to pharmacokinetic studies (BMRC)

Biomed Chromatogr. 23(6):568-72, 2009 Jun [LINK]

2009-International

· International Warfarin Pharmacogenetics Consortium, Klein TE, Altman RB, Eriksson N, Gage BF, Kimmel SE, Lee MT, Limdi NA, Page D, Roden DM, Wagner MJ, Caldwell MD, Johnson JA

Estimation of the warfarin dose with clinical and pharmacogenetic data (BMRC, PRCDM)

N Engl J Med. 360(8):753-64, 2009 Feb 19 [LINK]

2009-International

· Kim HS, Lee SS, Oh M, Jang YJ, Kim EY, Han IY, Cho KH, Shin JG

Effect of CYP2C9 and VKORC1 genotypes on early-phase and steady-state warfarin dosing in Korean patients with mechanical heart valve replacement (BMRC, PRCDM)

Pharmacogenet Genomics 19(2):103-12, 2009 Feb [LINK]

2008-International

· Ku HY, Shon JH, Liu KH, Shin JG, Bae SK

Liquid chromatography/tandem mass spectrometry method for the simultaneous determination of vardenafil and its major metabolite, N-desethylvardenafil, in human plasma: Application to a pharmacokinetic study (RCTC, BMRC)

J Chromatogr B Analyt Technol Biomed Life Sci. 877(1-2):95-100, 2009 Jan [LINK]

· Ryu MJ, Cho M, Song JY, Yun YS, Choi IW, Kim DE, Park BS, Oh S

Natural derivatives of curcumin attenuate the Wnt/beta-catenin pathway through down-regulation of the transcriptional coactivator p300 ()

Biochem Biophys Res Commun. 377(4):1304-8, 2008 Dec [LINK]

2008-International

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