Members
About PGRC
분류 |
교수 |
성명 |
이수준 |
성명(영문/한자) |
Su-Jun Lee / 李秀俊 |
소속 |
약리학교실 |
직위 |
교수 |
주요 학력 |
강원대학교 생화학 학사
강원대학교 생화학 석사 Oregon State University (USA) 독성학 박사 NIH (USA) 박사후 연구원 |
주요 연구 분야 |
1. SNP 분석 및 기능유전체학
2. 약물유전체학 3. 독성학 / 분자생물학 |
참조파일 |
파일없음 |
주요 경력
| 년 도 | 기 관 | 직위 (직명) |
| 2006.7 ~ 현재 | 인제대학교 약물유전체연구센터 | 전임강사 |
| 2001. 8 ~ 2006. 7 | National Institutes of Health | Post-doc |
연구 실적
| 학술지 논문발표 |
| 학회 발표 |
| 특허 |
| 기타 연구 실적 |
주요 연구 논문
| 1. Lee SJ, Coulter S, Jetten AM, and Goldstein, JA (2006). Identification and
functional studies of human CYP26A1 Single Nucleotide Polymorphisms (SNPs) in racially diverse populations. In Press. Pharmacogenetics and Genomics. 2. Lee SJ, Heiden IP, Goldstein JA, and Schaik RHN (2006) A new CYP3A5 variant, CYP3A5*11, is shown to be defective in nifedipine metabolism in a recombinant cDNA expression system. In Press. Drug Metabolism and Disposition. 3. Lee SJ, Jusko WJ, Salita CG, Calis KA, Jann MW, Spratlin VE, Goldstein JA, and Hon YH (2006). Reduced methylprednisolone clearance causing prolonged pharmacodynamics in a healthy subject was not associated with CYP3A5*3 allele or a change in diet composition. Journal of Clinical Pharmacology. 46, 515-526. 4. Lee SJ* and Goldstein JA (2005). Functionally defective or altered human CYP3A4 and CYP3A5 single nucleotide polymorphisms (SNPs) and their detections with genotyping tests. *Invited review. Pharmacogenomics. 6, 357-371. 5. Lee SJ, Bell DA, Coulter SJ, Ghanayem B, and Goldstein JA (2005). Recombinant CYP3A4*17 is defective in metabolizing the hypertensive drug nifedipine and the CYP3A4*17 allele may occur on the same chromosome as CYP3A5*3 representing a new putative defective CYP3A haplotype. Journal of Pharmacology and Experimental Therapeutics. 313, 302-309. 6. Blaisdell J, Jorge-Nebert LF, Coulter SJ, Ferguson SS, Lee SJ, Chanas B, Xi T, Mohrenweiser M, Ghanayem B, and Goldstein JA (2004). Discovery of new potentially defective alleles of human CYP2C9. Pharmacogenetics. 14, 527-37. 7. Lee SJ, Usmani K, Chanas B, Ghanayem B, Tina, Xi, Hodgson E, Mohrenweiser HW, and Goldstein JA (2003). Genetic findings and functional studies of human CYP3A5 single nucleotide polymorphisms in different ethnic groups. Pharmacogenetics. 13, 461- 472. |
주요 연구 과제 수행 실적
| 과제명 | 사업 명 | 주관 부처 | 연구기간 |
